Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605786 | 0.72 | EGFR (0.36) | TSHRMAPTCYP2C9LMNAATM | |
| SCHEMBL30497767 | 0.72 | TSHR (0.69) | CYP1A2TSHRMAPTGRM2CYP2C9 | |
| SCHEMBL5921179 | 0.69 | CYP2C9 (0.38) | CYP1A2MAPTPOLBGRM2CYP2C9 | |
| SCHEMBL30483907 | 0.66 | CYP1A2 (1.00) | CYP1A2TSHRCPA1CPB1CPA3 | |
| SCHEMBL5275777 | 0.66 | CYP1A2 (1.00) | CYP1A2TSHRCPA1CPB1CPA3 | |
| SCHEMBL5473567 | 0.65 | ATM (0.47) | TSHRMAPTCYP2C9LMNAATM | |
| SCHEMBL307459 | 0.65 | MAOA (0.34) | — | |
| SCHEMBL7956194 | 0.61 | CYP1A2 (0.53) | CYP1A2TSHR | |
| SCHEMBL7956197 | 0.61 | CYP1A2 (0.53) | CYP1A2TSHR | |
| SCHEMBL11793574 | 0.60 | L3MBTL1 (0.51) | CYP1A2TSHRMAPTGRM2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |