⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252054 | 0.77 | — | — | |
| SCHEMBL6627970 | 0.75 | — | — | |
| SCHEMBL348022 | 0.71 | — | — | |
| SCHEMBL4026102 | 0.69 | — | — | |
| SCHEMBL4026100 | 0.66 | — | — | |
| SCHEMBL6982635 | 0.65 | — | — | |
| SCHEMBL23260681 | 0.65 | ICMT (0.35) | — | |
| SCHEMBL6985622 | 0.62 | — | — | |
| SCHEMBL15100188 | 0.61 | PDE4A (0.32) | — | |
| SCHEMBL6981521 | 0.60 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207207-B2 | Heterocyclic a amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-26 | — | — | US | disclosed |
| US-8183416-B2 | Heterocyclic amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-7994093-B2 | Heterocyclocarboxamide derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| EP-1940813-B1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-7732469-B2 | for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| US-20100010063-A1 | HETEROCYCLOCARBOXAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-7598395-B2 | Tricyclic amine derivatives such as 3-Difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-isopropyl-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide; fungicides; horticulture | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| US-20080051446-A1 | Heterocyclocarboxamide Derivatives | SYNGENTA CROP PROTECTION, INC. | 2008-02-28 | — | — | US | disclosed |