Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465581 | 0.87 | MAPT (0.56) | MAPTKMT2AKCNN4HTTKCNE1 | |
| SCHEMBL506977 | 0.82 | TAAR1 (0.52) | KCNN4TAAR1PTPN1KIF11CA1 | |
| Hydrochloric Acid SCHEMBL9280100 | 0.80 | TAAR1 (0.50) | KCNN4TAAR1PTPN1KIF11CA1 | |
| SCHEMBL28733068 | 0.74 | MAPT (0.47) | MAPTKMT2AKCNN4HTTKCNE1 | |
| SCHEMBL16212235 | 0.73 | PTPN1 (0.47) | MAPTKMT2AKCNN4HTTPTPN1 | |
| Choline SCHEMBL15993997 | 0.72 | LMNA (0.43) | MAPTKMT2AKCNN4HTTKDM4E | |
| SCHEMBL28140828 | 0.71 | MAPT (0.52) | MAPTKMT2AKCNN4HTTTAAR1 | |
| SCHEMBL19566546 | 0.71 | KIF11 (0.58) | TAAR1PTPN1KIF11 | |
| SCHEMBL23588020 | 0.70 | KIF11 (0.55) | KMT2AKCNN4PTPN1KIF11KDM4E | |
| SCHEMBL17968493 | 0.70 | MAPT (0.56) | MAPTKMT2AKCNN4HTTKCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303510-A2 | CYCLIC OXYGUANIDINE PYRAZINONES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006248-A2 | CYCLIC OXYGUANIDINE PYRAZINONES AS PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |