Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980681 | 0.93 | F10 (0.45) | F10USP2HTTSMN1; SMN2PTGS2 | |
| SCHEMBL6985663 | 0.93 | F10 (0.45) | F10SMN1; SMN2PTGS2 | |
| SCHEMBL6989555 | 0.92 | F10 (0.43) | F10HTTPTGS2 | |
| SCHEMBL4680797 | 0.91 | F10 (0.49) | F10USP2HTTSMN1; SMN2PTGS2 | |
| SCHEMBL6985447 | 0.90 | F10 (0.45) | F10PTGS2 | |
| SCHEMBL6988024 | 0.87 | F10 (0.45) | F10SMN1; SMN2ACLY | |
| SCHEMBL6992512 | 0.84 | F10 (0.46) | F10 | |
| SCHEMBL4680260 | 0.83 | F10 (0.53) | F10 | |
| SCHEMBL6982192 | 0.83 | F10 (0.38) | F10USP2SMN1; SMN2ACLY | |
| SCHEMBL6990370 | 0.83 | ALDH1A1 (0.36) | F10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337251-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002102380-A1 | MONOCYCLIC OR BICYCLIC CARBOCYCLES AND HETEROCYCLES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-12-27 | — | — | WO | disclosed |