Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697370 | 0.90 | CYP19A1 (0.51) | CYP19A1CASRTSHRMDM2KMT2A | |
| SCHEMBL699118 | 0.88 | CYP19A1 (0.50) | CYP19A1CASRTSHRMDM2KMT2A | |
| SCHEMBL698788 | 0.85 | CYP19A1 (0.47) | CYP19A1MDM2KMT2AMEN1MRGPRX4 | |
| SCHEMBL27753898 | 0.84 | CYP19A1 (0.46) | CYP19A1CASRMDM2PTGESMRGPRX4 | |
| SCHEMBL27753970 | 0.84 | CYP19A1 (0.46) | CYP19A1CASRMDM2PTGESF2RL1 | |
| SCHEMBL697717 | 0.81 | CYP19A1 (0.51) | CYP19A1MDM2KMT2AMEN1ADRA2A | |
| SCHEMBL11670141 | 0.79 | CYP19A1 (0.41) | CYP19A1HDAC1KMT2AMEN1MRGPRX4 | |
| SCHEMBL697816 | 0.78 | CYP19A1 (0.51) | CYP19A1CASRTSHRMDM2KMT2A | |
| SCHEMBL697864 | 0.78 | CYP19A1 (0.48) | CYP19A1CASRHDAC3HDAC1HDAC2 | |
| SCHEMBL696482 | 0.78 | CYP19A1 (0.44) | CYP19A1MDM2KMT2APTGESADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |