Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914818 | 0.88 | CYP19A1 (0.51) | CYP19A1NPC1RAB9ACCR2MAPK1 | |
| SCHEMBL697512 | 0.88 | CYP19A1 (0.51) | CYP19A1NPC1RAB9ACCR2MAPK1 | |
| SCHEMBL696482 | 0.88 | CYP19A1 (0.44) | CYP19A1NPC1RAB9ACCR2ALDH1A1 | |
| SCHEMBL697855 | 0.83 | CYP19A1 (0.40) | CYP19A1MAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL28775053 | 0.82 | CYP19A1 (0.40) | CYP19A1MDM2PTGESIDO1 | |
| SCHEMBL6299558 | 0.82 | CYP19A1 (0.46) | CYP19A1RAB9AMAPK1CYP3A4CYP1A2 | |
| SCHEMBL698661 | 0.78 | CYP19A1 (0.53) | CYP19A1NPC1RAB9AMDM2MEN1 | |
| SCHEMBL697370 | 0.77 | CYP19A1 (0.51) | CYP19A1ALDH1A1MDM2MEN1KMT2A | |
| SCHEMBL706070 | 0.77 | CYP19A1 (0.48) | CYP19A1MAPK1CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL697717 | 0.77 | CYP19A1 (0.51) | CYP19A1CYP3A4MDM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |