Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986429 | 0.82 | MCHR1 (0.39) | GAAKMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6723581 | 0.72 | ELANE (0.44) | SLC7A5KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6984283 | 0.72 | SLC7A5 (0.38) | SLC7A5KDM4EGAAKMT2AMEN1 | |
| SCHEMBL6981189 | 0.71 | SLC7A5 (0.37) | SLC7A5KDM4EGAAKMT2ASMN1; SMN2 | |
| SCHEMBL6981261 | 0.71 | SLC7A5 (0.37) | SLC7A5KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6582605 | 0.71 | SLC7A5 (0.37) | SLC7A5KDM4EKMT2AMEN1MAPT | |
| SCHEMBL6984597 | 0.71 | KMT2A (0.42) | SLC7A5KDM4EGAAKMT2ASMN1; SMN2 | |
| SCHEMBL6985061 | 0.70 | ELANE (0.46) | ALOX15KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4312684 | 0.70 | MGAM (0.56) | KDM4EGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6985192 | 0.70 | KMT2A (0.42) | SLC7A5KDM4EGAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289953-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096304-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |