Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723581 | 0.87 | ELANE (0.44) | SLC7A5ELANEMEN1KMT2AALDH1A1 | |
| SCHEMBL6981261 | 0.85 | SLC7A5 (0.37) | SLC7A5EPHX2ARELANEMEN1 | |
| SCHEMBL6582605 | 0.85 | SLC7A5 (0.37) | SLC7A5EPHX2ARELANEMEN1 | |
| SCHEMBL6985192 | 0.84 | KMT2A (0.42) | SLC7A5MEN1KMT2AALDH1A1GAA | |
| SCHEMBL6988917 | 0.83 | SLC7A5 (0.36) | SLC7A5EPHX2ARELANEMEN1 | |
| SCHEMBL6985172 | 0.83 | AR (0.36) | SLC7A5EPHX2ARELANEMEN1 | |
| SCHEMBL6984974 | 0.80 | SLC6A3 (0.40) | SLC7A5EPHX2KMT2AALDH1A1KDM4E | |
| SCHEMBL4962205 | 0.79 | GRM6 (0.38) | GRM6ARELANEMEN1KMT2A | |
| SCHEMBL9103077 | 0.79 | GRM6 (0.38) | GRM6ARELANEMEN1KMT2A | |
| SCHEMBL6984002 | 0.77 | SMN1; SMN2 (0.40) | SLC7A5MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |