Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 7/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604172 | 0.95 | NPY5R (0.45) | NPY5RHTR4EZH2POLBHTT | |
| SCHEMBL6983375 | 0.90 | NPY5R (0.44) | NPY5RHTR4EZH2POLBHTT | |
| SCHEMBL6990117 | 0.86 | NPY5R (0.44) | NPY5RHTR4EZH2POLBHTR3E | |
| SCHEMBL6987001 | 0.81 | NPY5R (0.42) | NPY5RHTR4EZH2POLBHTR3E | |
| SCHEMBL6990590 | 0.78 | NPY5R (0.40) | NPY5RHTR4EZH2HTR3EHTR3B | |
| SCHEMBL6826776 | 0.77 | NPY5R (0.49) | NPY5RPOLBMEN1CYP1A2CYP3A4 | |
| SCHEMBL6829077 | 0.74 | NPY5R (0.61) | NPY5RHTR4POLB | |
| SCHEMBL6829078 | 0.65 | NPY5R (0.63) | NPY5RPOLBMEN1KMT2A | |
| SCHEMBL13735123 | 0.65 | SLC6A4 (0.39) | HTTHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6823457 | 0.64 | NPY5R (0.62) | NPY5RPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |