Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432202 | 0.81 | USP2 (1.00) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL6987102 | 0.80 | USP2 (0.72) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL1399530 | 0.80 | USP2 (0.72) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL29392319 | 0.80 | USP2 (0.77) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL11625657 | 0.80 | USP2 (0.72) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL13161966 | 0.80 | USP2 (0.72) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL15966072 | 0.78 | ALDH1A1 (0.76) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL10352600 | 0.78 | HPGD (0.73) | USP2HPGDTSHRHTTKMT2A | |
| SCHEMBL31171316 | 0.77 | KMT2A (0.65) | HPGDMAPK14HTTKMT2AALDH1A1 | |
| SCHEMBL7535584 | 0.77 | USP2 (0.68) | USP2HPGDTSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |