Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 12/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 6/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544456 | 1.00 | TGM2 (0.52) | TGM2CTSLHDAC1HDAC2CTSB | |
| SCHEMBL2861817 | 0.95 | TGM2 (0.55) | TGM2CTSLHDAC1HDAC2CTSB | |
| SCHEMBL2861823 | 0.95 | TGM2 (0.55) | TGM2CTSLHDAC1HDAC2CTSB | |
| SCHEMBL11100666 | 0.80 | TGM2 (0.60) | TGM2CTSLHDAC1HDAC2CTSB | |
| SCHEMBL8713258 | 0.79 | CTSL (0.65) | TGM2CTSLCTSBITGB3 | |
| SCHEMBL951558 | 0.79 | CTSL (0.65) | TGM2CTSLCTSBITGB3 | |
| SCHEMBL11144067 | 0.79 | CTSL (0.65) | TGM2CTSLCTSBITGB3 | |
| SCHEMBL11138908 | 0.79 | CTSL (0.65) | TGM2CTSLCTSBITGB3 | |
| SCHEMBL2487005 | 0.78 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL1796250 | 0.78 | CTSL (0.65) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268469-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070736-A1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |