Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988734 | 0.85 | CYP1A2 (0.41) | CYP1A2ACACBKMT2AMMP2MMP9 | |
| SCHEMBL6988727 | 0.85 | CYP1A2 (0.41) | CYP1A2ACACBKMT2AMMP2MMP9 | |
| SCHEMBL6989198 | 0.81 | CYP1A2 (0.43) | CYP1A2KMT2AMMP2MMP9MEN1 | |
| Hydrochloric Acid SCHEMBL6985055 | 0.80 | CYP1A2 (0.42) | CYP1A2KMT2AMMP2MMP9MEN1 | |
| SCHEMBL6987897 | 0.80 | MMP2 (0.35) | CYP1A2ACACBKMT2AMMP2MMP9 | |
| SCHEMBL6607764 | 0.79 | MMP2 (0.38) | CYP1A2ACACBKMT2AMMP2MMP9 | |
| SCHEMBL6607771 | 0.79 | MMP2 (0.38) | CYP1A2ACACBKMT2AMMP2MMP9 | |
| SCHEMBL6404062 | 0.79 | CYP1A2 (0.38) | CYP1A2ACACBKMT2AMMP2MEN1 | |
| SCHEMBL6404069 | 0.79 | CYP1A2 (0.38) | CYP1A2ACACBKMT2AMMP2MEN1 | |
| SCHEMBL6609601 | 0.79 | CYP1A2 (0.39) | CYP1A2ACACBKMT2AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |