Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985055 | 0.99 | CYP1A2 (0.42) | CYP1A2PDE10ACA12CA1CA2 | |
| SCHEMBL6988727 | 0.85 | CYP1A2 (0.41) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL6988734 | 0.85 | CYP1A2 (0.41) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL27578438 | 0.82 | TRPV1 (0.44) | CYP1A2PDE10AHIF1AEPAS1KMT2A | |
| SCHEMBL6987672 | 0.82 | HDAC3 (0.38) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL6987677 | 0.82 | HDAC3 (0.38) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL6987203 | 0.81 | CYP1A2 (0.38) | CYP1A2PDE10AHIF1AEPAS1MMP9 | |
| SCHEMBL6988573 | 0.80 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL6989193 | 0.78 | CYP1A2 (0.43) | CYP1A2PDE10ACA12CA1CA2 | |
| SCHEMBL6982449 | 0.77 | HIF1A (0.35) | CYP1A2PDE10AHIF1AEPAS1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |