Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206358 | 0.95 | LMNA (0.51) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL5789381 | 0.84 | LMNA (0.66) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL2481397 | 0.84 | LMNA (0.66) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL9621303 | 0.84 | LMNA (0.66) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL11607067 | 0.82 | LMNA (0.49) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL10363482 | 0.80 | CYP2C9 (0.53) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL10363481 | 0.80 | CYP2C9 (0.53) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| P-Cresol SCHEMBL6986663 | 0.80 | LMNA (0.61) | LMNAL3MBTL1ESR2ALDH2KMT2A | |
| SCHEMBL11363959 | 0.80 | SMN1; SMN2 (0.45) | LMNAL3MBTL1ESR2KMT2AALDH1A1 | |
| SCHEMBL11517754 | 0.78 | SMN1; SMN2 (0.62) | L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |