Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621303 | 0.95 | LMNA (0.66) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL5789381 | 0.95 | LMNA (0.66) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL2481397 | 0.95 | LMNA (0.66) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL18562096 | 0.93 | LMNA (0.63) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL5205374 | 0.93 | LMNA (0.63) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL9857703 | 0.83 | LMNA (0.63) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL9063261 | 0.83 | LMNA (0.63) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL11548487 | 0.83 | L3MBTL1 (0.63) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL10430413 | 0.83 | LMNA (0.52) | LMNAL3MBTL1KMT2AALDH2MEN1 | |
| SCHEMBL10387518 | 0.82 | TSHR (0.53) | LMNAL3MBTL1KMT2AALDH2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |