SCHEMBL6987286

SCHEMBL6987286

CN(C)C(=O)NC(=O)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 3/20 0.44
APEX1 P27695 2/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 1/20 0.39
PMP22 Q01453 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA4 P43681 1/20 0.39
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28070339 0.89 KMT2A (0.40) ALDH1A1TSHRKMT2A
SCHEMBL8279656 0.87
SCHEMBL10072428 0.87
SCHEMBL11474727 0.84
SCHEMBL375911 0.84
SCHEMBL14267758 0.82 ALDH1A1 (0.34) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL12800872 0.82
SCHEMBL5470221 0.80 ALDH1A1 (0.42) ALDH1A1TSHRAPEX1NFKB1THPO
SCHEMBL14198889 0.80 TSHR (0.33) ALDH1A1TSHRCHRNB2CHRNB4CHRNA4
SCHEMBL6195858 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7331665-B2 Inkjet recording method and inkjet recording apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-19 US disclosed
US-7328992-B2 Inkjet recording method and inkjet recording apparatus KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-12 US disclosed
US-20070052785-A1 INK-JET IMAGE FORMING METHOD KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2007-03-08 US disclosed
EP-1759858-A1 Ink-jet image forming method Konica Minolta Photo Imaging, Inc. (JP) 2007-03-07 EP disclosed
EP-1301480-A1 1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS ABBOTT LABORATORIES (US) 2003-04-16 EP disclosed
WO-2002006223-A1 1,3-DISUBSTITUTED AND 1,3,3-TRISUBSTITUTED PYRROLIDINES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS ABBOTT LABORATORIES (US) 2002-01-24 WO disclosed