⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987286 | 0.87 | ALDH1A1 (0.44) | — | |
| Benzene SCHEMBL28070339 | 0.84 | KMT2A (0.40) | — | |
| SCHEMBL10072428 | 0.75 | — | — | |
| SCHEMBL11474727 | 0.73 | — | — | |
| SCHEMBL375911 | 0.73 | — | — | |
| SCHEMBL23896083 | 0.73 | MTOR (0.32) | — | |
| SCHEMBL12800872 | 0.71 | — | — | |
| SCHEMBL14267758 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL5470221 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL14198889 | 0.69 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4035528-B1 | 7-OXA-3,4-DIAZABICYCLO[4.1.0]HEPT-4-EN-2-ONE COMPOUND AND HERBICIDE | NIPPON SODA CO (JP) | 2024-03-27 | — | — | EP | disclosed |
| CN-116981671-A | 7-oxa-3, 4-diazabicyclo [4.1.0] hept-4-en-2-one compounds and herbicides | 日本曹达株式会社 | 2023-10-31 | — | — | CN | disclosed |
| US-20220289758-A1 | 7-OXA-3,4-DIAZABICYCLO [4.1.0] HEPT-4-EN-2-ONE COMPOUND AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 2022-09-15 | — | — | US | disclosed |
| CN-109563509-B | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNAs | 菲奥医药公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-4035528-A1 | 7-OXA-3,4-DIAZABICYCLO[4.1.0]HEPTA-4-ENE-2-ONE COMPOUND AND HERBICIDE | Nippon Soda Co., Ltd. (JP) | 2022-08-03 | — | — | EP | disclosed |
| WO-2021060240-A1 | 7-OXA-3,4-DIAZABICYCLO[4.1.0]HEPTA-4-ENE-2-ONE COMPOUND AND HERBICIDE | 日本曹達株式会社 | 2021-04-01 | — | — | WO | disclosed |
| CN-111825733-A | Macrolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2020-10-27 | — | — | CN | disclosed |
| WO-2005085239-A2 | PYRROLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-09-15 | — | — | WO | disclosed |