Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996868 | 0.94 | KDM4E (0.51) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL11540114 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL8637757 | 0.87 | CA2 (0.61) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9808062 | 0.85 | TEAD1 (0.53) | KDM4EALDH1A1TEAD1YAP1TEAD4 | |
| SCHEMBL10916274 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1CA2TEAD1YAP1 | |
| SCHEMBL8955502 | 0.83 | HDAC3 (0.58) | KDM4EALDH1A1CA2TEAD1YAP1 | |
| SCHEMBL26116458 | 0.83 | HDAC3 (0.58) | KDM4EALDH1A1CA2TEAD1YAP1 | |
| SCHEMBL7018220 | 0.81 | CYP2A6 (0.43) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL3900894 | 0.80 | CA2 (0.55) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL9808069 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1TEAD1YAP1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58079970-A | — | — | None | — | — | JP | disclosed |
| CN-122039074-A | Method for preparing sulfoxide compound by electrochemical microchannel continuous flow oxidation | 南京工业大学 | 2026-05-15 | — | — | CN | disclosed |
| US-9657024-B2 | Substituted triazolo-pyrimidine compounds for modulating cell proliferation, differentiation and survival | STATEGICS, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2185562-B1 | PYRROLOPYRIMIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-02 | — | — | EP | disclosed |
| US-20150307498-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-10-29 | — | — | US | disclosed |
| US-9163027-B2 | Substituted triazolo-pyrimidine compounds for modulating cell proliferation differentiation and survival | STATEGICS, INC. (US) | 2015-10-20 | — | — | US | disclosed |
| EP-2922548-A2 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | Stategics, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081878-A2 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | STATEGICS, INC. (US) | 2014-05-30 | — | — | WO | disclosed |
| US-20140142122-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | STATEGICS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| EP-2562167-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2000023071-A9 | PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS | LEUKOSITE INC (US) | 2000-09-14 | — | — | WO | disclosed |
| WO-2000023071-A1 | PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS | LEUKOSITE, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |
| US-5141552-A | Applying isothiazole plant growth regulator to one variety, pollinating with another | UNIVERSITY PATENTS, INC. (US) | 1992-08-25 | — | — | US | disclosed |
| US-4937268-A | TREATMENT OF ASTHMA, CHRONIC BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0286242-A2 | Ethanolamine derivates, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |
| JP-S5879970-A | PROPIOLIC ACID ESTER | IHARA CHEM IND CO LTD | 1983-05-13 | — | — | JP | disclosed |
| US-4000315-A | Cyclopropane esters for the control of mites | ZOECON CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957849-A | MITICIDES | ZOECON CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142122-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | EPOR, THPO, MKI67 | KDM4E 2685/4885ALDH1A1 396/4885CA12 4827/4885 |
| US-20150307498-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | EPOR, THPO, MKI67 | KDM4E 2685/4885ALDH1A1 396/4885CA12 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.