Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989868 | 0.82 | PAX8 (0.60) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| SCHEMBL6999642 | 0.82 | PAX8 (0.60) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| SCHEMBL6989105 | 0.82 | GSK3A (0.52) | MAPK1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL6991542 | 0.81 | PAX8 (0.59) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL6989457 | 0.80 | PAX8 (0.58) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL6992480 | 0.77 | PAX8 (0.54) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| SCHEMBL6994180 | 0.76 | ALDH1A1 (0.34) | ALDH1A1KMT2AMAPT | |
| SCHEMBL4400604 | 0.76 | PAX8 (1.00) | PAX8MAPK1OPRK1RAB9ANPSR1 | |
| SCHEMBL6994508 | 0.75 | MAPT (0.32) | KDM4EKMT2AMAPT | |
| SCHEMBL6996186 | 0.72 | GSK3B (0.52) | ALDH1A1KMT2ALMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |