Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.62 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988324 | 0.91 | AVPR1A (0.60) | AVPR1AAVPR1BLMNATP53AVPR2 | |
| SCHEMBL6986447 | 0.88 | AVPR1A (0.71) | AVPR1AAVPR1BTHRBKCNQ2AVPR2 | |
| SCHEMBL6992463 | 0.84 | AVPR1A (0.55) | AVPR1AAVPR1BKCNQ2LMNATP53 | |
| SCHEMBL6984078 | 0.82 | AVPR1A (0.69) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991697 | 0.80 | AVPR1A (0.74) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6992414 | 0.79 | AVPR1A (0.66) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991577 | 0.78 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6986061 | 0.78 | AVPR1A (0.77) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991880 | 0.77 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6991584 | 0.77 | AVPR1A (0.72) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | claimed |
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | claimed |
| WO-1996022294-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |