Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.55 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988324 | 0.86 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6987453 | 0.84 | AVPR1A (0.62) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6987246 | 0.84 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTRMEN1 | |
| SCHEMBL6989949 | 0.81 | AVPR1A (0.62) | AVPR1AAVPR1BAVPR2OXTRMEN1 | |
| SCHEMBL6990890 | 0.78 | AVPR1A (0.66) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6987460 | 0.78 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2OXTRMEN1 | |
| SCHEMBL6986447 | 0.78 | AVPR1A (0.71) | AVPR1AAVPR1BAVPR2KCNQ2MEN1 | |
| SCHEMBL7091449 | 0.78 | AVPR1A (0.65) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6991880 | 0.77 | AVPR1A (0.67) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6991577 | 0.76 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |