Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.39 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18172020 | 0.82 | GAA (0.47) | NR3C2MAPK14L3MBTL1NPSR1KMT2A | |
| SCHEMBL8195234 | 0.80 | SMN1; SMN2 (0.43) | NR3C2NPSR1KMT2AALDH1A1MEN1 | |
| SCHEMBL15442145 | 0.76 | KCNN4 (0.48) | NR3C2MAPK14MGLLUGCGKCNN4 | |
| SCHEMBL25956786 | 0.74 | NR3C2 (0.50) | NR3C2MAPK14L3MBTL1HSD11B1MGLL | |
| SCHEMBL30447578 | 0.74 | NR3C2 (0.50) | NR3C2MAPK14L3MBTL1HSD11B1MGLL | |
| SCHEMBL1491079 | 0.74 | POLB (0.50) | NR3C2MAPK14MGLLSCN5ASCN9A | |
| SCHEMBL31468347 | 0.74 | POLB (0.50) | NR3C2MAPK14MGLLSCN5ASCN9A | |
| SCHEMBL16815703 | 0.74 | KCNN4 (0.47) | NR3C2MAPK14HSD11B1MGLLKCNN4 | |
| SCHEMBL10242690 | 0.74 | MAPK1 (0.51) | ALDH1A1 | |
| SCHEMBL16815353 | 0.71 | MAPK14 (0.42) | NR3C2MAPK14HSD11B1MGLLUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |