Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687949 | 0.83 | DPP7 (0.47) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL19687950 | 0.83 | DPP7 (0.47) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL14315876 | 0.83 | DPP7 (0.47) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL3781423 | 0.79 | NOS2 (0.39) | PRCPDPP7TLR2HTR2CCYP1A2 | |
| SCHEMBL3781419 | 0.79 | NOS2 (0.39) | PRCPDPP7TLR2HTR2CCYP1A2 | |
| SCHEMBL21105823 | 0.77 | PRCP (0.56) | PRCPDPP7TLR2 | |
| SCHEMBL28014192 | 0.77 | DPP7 (0.53) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL14887225 | 0.76 | PRCP (0.44) | PRCPDPP7TLR2HTR2CCYP1A2 | |
| SCHEMBL14887354 | 0.76 | PRCP (0.44) | PRCPDPP7TLR2HTR2CCYP1A2 | |
| SCHEMBL14887236 | 0.76 | PRCP (0.44) | PRCPDPP7TLR2HTR2CCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315698-A1 | PYRROLIDINES AS INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-1999054299-A1 | PYRROLIDINES AS INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 1999-10-28 | — | — | WO | disclosed |