Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 3/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105823 | 0.80 | PRCP (0.56) | DPP7PRCPTLR2SLC6A3DRD3 | |
| SCHEMBL27972502 | 0.79 | DPP7 (0.49) | DPP7PRCPTLR2SIGMAR1CTSK | |
| SCHEMBL19687949 | 0.78 | DPP7 (0.47) | DPP7PRCPTLR2CTSKCTSL | |
| SCHEMBL19687950 | 0.78 | DPP7 (0.47) | DPP7PRCPTLR2CTSKCTSL | |
| SCHEMBL14315876 | 0.78 | DPP7 (0.47) | DPP7PRCPTLR2CTSKCTSL | |
| SCHEMBL27558572 | 0.77 | EPHX2 (0.41) | DPP7CTSKCTSLCTSBMETAP1 | |
| SCHEMBL27345589 | 0.77 | CTSK (0.40) | SIGMAR1CTSKCTSLCTSBMETAP1 | |
| SCHEMBL27276206 | 0.77 | EPHX2 (0.35) | CTSKCTSLCTSBCYP3A4METAP1 | |
| SCHEMBL6987475 | 0.77 | PRCP (0.48) | DPP7PRCPTLR2CYP1A2CYP3A4 | |
| SCHEMBL3771163 | 0.76 | NOS2 (0.39) | DPP7PRCPTLR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864252-B | Method for preparing NRX-1074 | 中国人民解放军军事科学院军事医学研究院 | 2020-07-28 | — | — | CN | claimed |
| CN-108864252-A | The method for preparing NRX-1074 | 中国人民解放军军事科学院军事医学研究院 | 2018-11-23 | — | — | CN | claimed |
| CN-105859719-A | Preparation method of anti-tumor active compound | 华东理工大学 | 2016-08-17 | — | — | CN | claimed |
| CN-108864252-B | Method for preparing NRX-1074 | 中国人民解放军军事科学院军事医学研究院 | 2020-07-28 | — | — | CN | disclosed |
| CN-109020977-A | A kind of preparation method of Acalabrutinib | 安庆奇创药业有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-108864252-A | The method for preparing NRX-1074 | 中国人民解放军军事科学院军事医学研究院 | 2018-11-23 | — | — | CN | disclosed |
| CN-105859719-A | Preparation method of anti-tumor active compound | 华东理工大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104607163-A | Micro-chiral adjusting cellulose chromatography stationary phase, as well as preparation method and application thereof | BEIJING SCIENCE & TECH | 2015-05-13 | — | — | CN | disclosed |