Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 4/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065460 | 0.82 | FPR2 (0.53) | GPR119FPR2FPR1MEN1KMT2A | |
| SCHEMBL7065465 | 0.82 | FPR2 (0.53) | GPR119FPR2FPR1MEN1KMT2A | |
| SCHEMBL4209706 | 0.78 | NPC1 (0.53) | MEN1KMT2ANPC1PTPN2PTPN1 | |
| SCHEMBL7065090 | 0.77 | FPR2 (0.49) | GPR119FPR2FPR1L3MBTL1POLB | |
| SCHEMBL3831783 | 0.75 | NPC1 (0.64) | FPR2MEN1KMT2ANPC1PTPN2 | |
| SCHEMBL3833239 | 0.75 | GPR119 (0.51) | GPR119FPR2FPR1MEN1KMT2A | |
| SCHEMBL7064874 | 0.74 | FPR2 (0.48) | GPR119FPR2FPR1LMNAL3MBTL1 | |
| SCHEMBL7065471 | 0.73 | FPR2 (0.48) | GPR119FPR2FPR1F10 | |
| SCHEMBL7065095 | 0.73 | FPR2 (0.48) | GPR119FPR2FPR1F10 | |
| SCHEMBL7064681 | 0.73 | PRSS1 (0.50) | FPR2FPR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301506-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006269-A1 | CYCLIC AMINO ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-24 | — | — | WO | disclosed |