Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15763906 | 0.85 | MEN1 (0.52) | MEN1KMT2AALDH1A1HPGDESR1 | |
| SCHEMBL27821595 | 0.84 | MEN1 (0.51) | MEN1KMT2AALDH1A1HPGDESR1 | |
| SCHEMBL22265088 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDESR1 | |
| SCHEMBL29852392 | 0.82 | ACHE (0.61) | MEN1KMT2AALDH1A1HPGDESR1 | |
| SCHEMBL1021094 | 0.82 | ACHE (0.61) | MEN1KMT2AALDH1A1HPGDESR1 | |
| Hydrochloric Acid SCHEMBL27841047 | 0.81 | TAAR1 (0.53) | MEN1KMT2AALDH1A1HPGDESR2 | |
| SCHEMBL27555828 | 0.81 | CYP4F2 (0.44) | MEN1KMT2AALDH1A1HPGDCES2 | |
| SCHEMBL20335031 | 0.80 | LMNA (0.65) | MEN1KMT2AALDH1A1PPARGACHE | |
| SCHEMBL4633863 | 0.80 | CYP3A4 (0.59) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL27771513 | 0.80 | CYP3A4 (0.47) | MEN1KMT2AALDH1A1ACHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283439-B | The dibenzoylhydrazine of boracic | 英特瑞克斯顿股份有限公司 | 2018-02-02 | — | — | CN | disclosed |
| EP-3194359-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | Intrexon Corporation (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044390-A1 | BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS | INTREXON CORPORATION (US) | 2016-03-24 | — | — | WO | disclosed |
| CN-105283439-A | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP | 2016-01-27 | — | — | CN | disclosed |
| CN-102056927-B | Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors | IRM LLC | 2014-06-25 | — | — | CN | disclosed |
| CN-102056927-A | Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors | IRM LLC | 2011-05-11 | — | — | CN | disclosed |
| CN-101104862-B | Method for synthesizing D-arylglycine by using heterogeneous enzyme to catalytically hydrolyzing 5-arylhydantoin | UNIV HEBEI SCIENCE & TECH | 2010-05-19 | — | — | CN | disclosed |
| CN-101627007-A | Aminoamides as orexin antagonists | HOFFMANN LA ROCHE | 2010-01-13 | — | — | CN | disclosed |
| CN-100398555-C | Protease inhibitors for coronaviruses and SARS-COV and the use thereof | CYTOVIA INC (US) | 2008-07-02 | — | — | CN | disclosed |
| CN-101104862-A | Method for synthesizing D-arylglycine by using heterogeneous enzyme to catalytically hydrolyzing 5-arylhydantoin | UNIV HEBEI SCIENCE & TECH (CN) | 2008-01-16 | — | — | CN | disclosed |
| CN-1984909-A | Thiazolinone unsubstituted quinolines | HOFFMANN LA ROCHE (CH) | 2007-06-20 | — | — | CN | disclosed |
| CN-1784239-A | Protease inhibitors of coronavirus and SARS-COV and use thereof | CYTOVIA INC (US) | 2006-06-07 | — | — | CN | disclosed |
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| CN-1297354-A | Dipeptide caspase inhibitors and use thereof | CYTOVIA INC (US) | 2001-05-30 | — | — | CN | disclosed |