Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125838 | 0.82 | KDM4E (0.35) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6992857 | 0.82 | MEN1 (0.38) | ALDH1A1 | |
| SCHEMBL9412508 | 0.81 | TSHR (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8210030 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6988670 | 0.75 | TKT (0.31) | — | |
| SCHEMBL10645986 | 0.71 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9122750 | 0.70 | — | — | |
| SCHEMBL9127572 | 0.70 | PNP (0.37) | HSD17B10 | |
| SCHEMBL8205815 | 0.70 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8777016 | 0.69 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589335-B1 | N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means | HOECHST AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-5457091-A | N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0589335-A1 | N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-30 | — | — | EP | disclosed |