Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127572 | 0.82 | PNP (0.37) | TSHRHSD17B10HBB | |
| SCHEMBL9125838 | 0.82 | KDM4E (0.35) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6987870 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6992857 | 0.71 | MEN1 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8926305 | 0.70 | HSD17B10 (0.61) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9122750 | 0.68 | — | — | |
| SCHEMBL19770359 | 0.67 | KDM4E (0.35) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8210030 | 0.64 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11249941 | 0.63 | MEN1 (0.57) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9366819 | 0.62 | MEN1 (0.56) | TSHRMEN1KMT2AHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589335-A1 | N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-30 | — | — | EP | disclosed |