Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4837366 | 0.99 | FAAH (0.41) | FAAHALDH1A1TSHRHRH1PTGS2 | |
| SCHEMBL4836758 | 0.81 | TP53 (0.58) | FAAHALDH1A1TSHRKDM4E | |
| SCHEMBL4840912 | 0.79 | P2RX7 (0.53) | FAAHP2RX7 | |
| Hydrochloric Acid SCHEMBL4840698 | 0.78 | P2RX7 (0.52) | FAAHTSHRP2RX7 | |
| Hydrochloric Acid SCHEMBL4832771 | 0.78 | P2RX7 (0.52) | FAAHTSHRP2RX7 | |
| SCHEMBL4832913 | 0.78 | P2RX7 (0.46) | FAAHALDH1A1P2RX7KDM4EEGLN1 | |
| SCHEMBL4832750 | 0.76 | FAAH (0.43) | FAAHALDH1A1TSHRNPSR1KDM4E | |
| SCHEMBL4832544 | 0.76 | TP53 (0.43) | FAAHALDH1A1TSHRNPSR1P2RX7 | |
| SCHEMBL4836752 | 0.76 | KDM4E (0.54) | FAAHALDH1A1P2RX7KDM4E | |
| SCHEMBL13779963 | 0.75 | KDM1A (0.57) | ALDH1A1PTGS2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |