SCHEMBL6988010

SCHEMBL6988010

Cc1cccc(P(c2ccccc2)c2ccccc2)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
CYP3A4 P08684 2/20 0.46
DRD1 P21728 2/20 0.44
TRPA1 O75762 2/20 0.38
ATM Q13315 1/20 0.38
TSHR P16473 3/20 0.38
ACHE P22303 1/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 3/20 0.33
CYP2A6 P11509 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.33
AKR1B10 O60218 1/20 0.33
ABCB11 O95342 1/20 0.33
DHFR P00374 1/20 0.33
LMNA P02545 1/20 0.33
MPO P05164 1/20 0.33
CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6843669 0.96 TDP1 (0.46) TDP1CYP3A4DRD1TRPA1ATM
SCHEMBL15660512 0.92 CYP3A4 (0.42) TDP1CYP3A4DRD1TRPA1ATM
SCHEMBL15657818 0.88 CYP3A4 (0.39) TDP1CYP3A4DRD1TRPA1ATM
SCHEMBL10981357 0.86 DRD1 (0.36) TDP1CYP3A4DRD1
SCHEMBL15656541 0.84 TSHR (0.43) TDP1CYP3A4TRPA1ATMTSHR
SCHEMBL49858 0.84 CYP3A4 (0.52) TDP1CYP3A4DRD1TSHRACHE
SCHEMBL126302 0.84 TRPA1 (0.46) CYP3A4TRPA1ATMTSHRACHE
SCHEMBL29706026 0.84 TRPA1 (0.46) CYP3A4TRPA1ATMTSHRACHE
SCHEMBL29653622 0.84 TRPA1 (0.46) CYP3A4TRPA1ATMTSHRACHE
SCHEMBL301645 0.83 TDP1 (0.46) TDP1CYP3A4DRD1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
CN-109153850-A Resin combination 株式会社艾迪科 2019-01-04 CN disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
CN-101636403-B Method for the production of an alkenyl phosphonic acid derivative BASF SE 2013-05-15 CN disclosed
WO-2012004352-A2 MESOPOROUS DIPHOSPHINE-TRANSITION METAL COMPLEX CATALYST FOR HYDROFORMYLATION STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2012-01-12 WO disclosed
CN-1207099-C catalyst system and carbonylation process BASF AG (DE) 2005-06-22 CN disclosed
EP-0174576-B1 HYDROGENATION OF UNSATURATED POLYMERS CONTAINING NITRILE GROUPS BAYER AG (DE) 1989-09-13 EP disclosed
US-4812587-A Process for selective hydrogenation of C--C double bonds in the presence of reducible, nitrogen-containing groups and new ruthenium complex compounds BAYER AKTIENGESELLSCHAFT (DE) 1989-03-14 US disclosed
EP-0138141-B1 PROCESS FOR THE SELECTIVE HYDROGENATION OF C-C DOUBLE BONDS IN THE PRESENCE OF REDUCIBLE NITROGEN-CONTAINING GROUPS BAYER AG (DE) 1988-02-24 EP disclosed
US-4673757-A Process for selective hydrogenation of C-C double bonds in the presence of reducible, nitrogen-containing groups and new ruthenium complex compounds BAYER AKTIENGESELLSCHAFT (DE) 1987-06-16 US disclosed
EP-0224139-A2 Process for the selective hydrogenation of unsaturated polymers containing nitrile groups BAYER AG (DE) 1987-06-03 EP disclosed
EP-0223151-A2 Process for the selective hydrogenation of unsaturated compounds BAYER AG (DE) 1987-05-27 EP disclosed
EP-0213422-A2 Process for the selective hydrogenation of unsaturated compounds BAYER AG (DE) 1987-03-11 EP disclosed
US-4631315-A RUTHENIUM HALOGEN PHOSPHANE COMPLEX CATALYST TO PRESERVE NITRILE GROUPS; RUBBERS BAYER AKTIENGESELLSCHAFT (DE) 1986-12-23 US disclosed
EP-0174576-A2 Hydrogenation of unsaturated polymers containing nitrile groups BAYER AG (DE) 1986-03-19 EP disclosed
EP-0138141-A1 Process for the selective hydrogenation of C-C double bonds in the presence of reducible nitrogen-containing groups BAYER AG (DE) 1985-04-24 EP disclosed