SCHEMBL6988236

SCHEMBL6988236

CC(C=O)=CC=Cc1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
TYR P14679 1/20 0.50
MAPK1 P28482 1/20 0.50
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
RAB9A P51151 6/20 0.43
NPC1 O15118 5/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
EGFR P00533 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
GRIK1 P39086 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6988234 1.00 KDM4E (0.50) KDM4ETYRMAPK1PTGS1PTGS2
SCHEMBL3686386 0.78 ALDH1A1 (0.59) KDM4ETYRMAPK1PTGS1PTGS2
SCHEMBL5599268 0.78 ALDH1A1 (0.59) KDM4EMAPK1SMN1; SMN2ALDH1A1LMNA
SCHEMBL3686385 0.78 ALDH1A1 (0.59) KDM4ETYRMAPK1PTGS1PTGS2
SCHEMBL5599265 0.78 ALDH1A1 (0.59) KDM4EMAPK1SMN1; SMN2ALDH1A1LMNA
SCHEMBL2833821 0.77 TYR (0.61) KDM4ETYRMAPK1PTGS1PTGS2
SCHEMBL2349983 0.77 TYR (0.61) KDM4ETYRMAPK1PTGS1PTGS2
SCHEMBL7799748 0.75 CYP1A2 (0.50) PTGS1PTGS2
SCHEMBL7799743 0.75 CYP1A2 (0.50) PTGS1PTGS2
SCHEMBL23918549 0.72 TYR (0.64) KDM4ETYRMAPK1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908439-B1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 2003-01-02 EP disclosed
EP-0908439-A1 Use of substituted 5-phenyl-pentanols as flavour and perfume HAARMANN & REIMER GMBH (DE) 1999-04-14 EP disclosed