Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686386 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL11478074 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL11478075 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL31380631 | 0.83 | TYR (0.52) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL31380633 | 0.83 | TYR (0.52) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL31380610 | 0.83 | TYR (0.52) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL31380603 | 0.83 | TYR (0.52) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL28221244 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL19554075 | 0.82 | TSHR (0.52) | ALDH1A1TSHRTYRKDM4EMAPK1 | |
| SCHEMBL4087610 | 0.79 | ALDH1A1 (0.63) | ALDH1A1TSHRMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957437-B1 | PROCESS FOR PRODUCING ALPHA,BETA-UNSATURATED ALDEHYDE COMPOUNDS | KAO CORP (JP) | 2017-05-03 | — | — | EP | disclosed |
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-9000192-B2 | Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8674144-B2 | Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20130217895-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-08-22 | — | — | US | disclosed |
| US-7732644-B2 | Process for producing α,β-unsaturated aldehyde compounds | KAO CORPORATION (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20090171124-A1 | PROCESS FOR PRODUCING ALPHA, BETA-UNSATURATED ALDEHYDE COMPOUNDS | KAO CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1957437-A1 | PROCESS FOR PRODUCING ALPHA,BETA-UNSATURATED ALDEHYDE COMPOUNDS | Kao Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063703-A1 | PROCESS FOR PRODUCING α,β-UNSATURATED ALDEHYDE COMPOUNDS | KAO CORPORATION (JP) | 2007-06-07 | — | — | WO | disclosed |
| EP-0185872-B1 | 1-PHENYL-2-METHYL-3-HYDROXY-(3-ACYLOXY)-ALKYL COMPOUNDS AND THEIR USE AS PERFUMES | BASF Aktiengesellschaft (DE) | 1990-02-07 | — | — | EP | disclosed |
| EP-0185872-A1 | 1-Phenyl-2-methyl-3-hydroxy-(3-acyloxy)-alkyl compounds and their use as perfumes | BASF Aktiengesellschaft (DE) | 1986-07-02 | — | — | EP | disclosed |
| EP-0017893-B1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC TERTIARY ARALKYL AMINES | BASF Aktiengesellschaft (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4318831-A | Polysubstituted cyclopentene derivatives | DRAGOCO GERBERDING & CO GMBH (DE) | 1982-03-09 | — | — | US | disclosed |
| US-4283534-A | Reductive alkylation of nitrogen heterocycles | BASF AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |
| US-4273945-A | HYDROGENATION OF UNSATURATED ALDEHYDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |
| EP-0017893-A1 | Process for the preparation of heterocyclic tertiary aralkyl amines | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171124-A1 | PROCESS FOR PRODUCING ALPHA, BETA-UNSATURATED ALDEHYDE COMPOUNDS | ADH1C, ADH1A, ADH5 | ALDH1A1 5/4885TSHR 4189/4885TYR 4555/4885 |
| US-20130217895-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | HMOX1, NQO1, CBR3 | ALDH1A1 61/4885TSHR 4820/4885TYR 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.