SCHEMBL69886

SCHEMBL69886

COC(=O)c1ccnc2c(C(=O)OC)cccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 2/20 0.73
KDM4E B2RXH2 8/20 0.63
SLC40A1 Q9NP59 3/20 0.60
MAP2K1 Q02750 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
KDM4A O75164 1/20 0.49
RAB9A P51151 1/20 0.49
EGLN1 Q9GZT9 1/20 0.49
HIF1AN Q9NWT6 1/20 0.49
ATM Q13315 2/20 0.46
POLB P06746 1/20 0.46
ALDH1A1 P00352 2/20 0.45
PKN1 Q16512 1/20 0.45
PKN2 Q16513 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7654796 0.92 PSMD14 (0.68) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1
SCHEMBL10383135 0.87 KDM4E (0.78) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1
SCHEMBL11431252 0.87 KDM4E (0.60) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1
SCHEMBL19642874 0.87 PSMD14 (0.69) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1
SCHEMBL31424218 0.87 KDM4E (0.78) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1
SCHEMBL23812317 0.86 PSMD14 (0.56) PSMD14KDM4ESLC40A1MAP2K1ATM
SCHEMBL17113200 0.86 PSMD14 (0.56) PSMD14KDM4ESLC40A1MAP2K1ATM
SCHEMBL23293688 0.86 PSMD14 (0.56) PSMD14KDM4ESLC40A1MAP2K1ATM
SCHEMBL11434003 0.86 PSMD14 (0.56) PSMD14KDM4ESLC40A1MAP2K1RAB9A
SCHEMBL22492423 0.86 PSMD14 (0.68) PSMD14KDM4ESLC40A1MAP2K1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PSMD14 291/4885KDM4E 717/4885SLC40A1 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.