Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69886 | 0.92 | PSMD14 (0.73) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL7370092 | 0.84 | NUDT1 (0.52) | PSMD14KDM4EKDM4ARAB9AALDH1A1 | |
| SCHEMBL19642874 | 0.83 | PSMD14 (0.69) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL31424218 | 0.83 | KDM4E (0.78) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL10383135 | 0.83 | KDM4E (0.78) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL7372534 | 0.83 | KDM4E (0.66) | PSMD14KDM4ESLC40A1L3MBTL1KDM4A | |
| SCHEMBL22492423 | 0.82 | PSMD14 (0.68) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL11973493 | 0.82 | PSMD14 (0.68) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL19642938 | 0.82 | PSMD14 (0.68) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 | |
| SCHEMBL7377364 | 0.82 | PSMD14 (0.68) | PSMD14KDM4ESLC40A1MAP2K1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |