SCHEMBL698874

SCHEMBL698874

CS(=O)(=O)NC(CC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.40
CA4 P22748 1/20 0.40
MME P08473 3/20 0.40
CA1 P00915 2/20 0.39
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
GNPAT O15228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698875 1.00 CA2 (0.40) CA2CA4MMECA1ITGB3
SCHEMBL715097 1.00 CA2 (0.40) CA2CA4MMECA1ITGB3
SCHEMBL3977107 0.83 ECE1 (0.44) CA2CA1ITGB3ITGA2B
SCHEMBL20335048 0.83 ECE1 (0.44) CA2CA1ITGB3ITGA2B
SCHEMBL20335047 0.83 ECE1 (0.44) CA2CA1ITGB3ITGA2B
SCHEMBL3977104 0.83 SCN9A (0.36) CA2CA1ITGB3ITGA2B
SCHEMBL12052343 0.82 MMP2 (0.39) MMEITGB3ITGA2BSMN1; SMN2
SCHEMBL13253140 0.81 CA2 (0.39) CA2CA4MMECA1TDP1
SCHEMBL714149 0.81 CA2 (0.39) CA2CA4MMECA1TDP1
SCHEMBL715191 0.81 CA2 (0.39) CA2CA4MMECA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423211-B1 PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF KANEKA CORP (JP) 2014-04-16 EP disclosed
EP-2423211-A1 PROCESSES FOR PRODUCING (1S,6S)- OR (1R,6R)-CIS-2,8-DIAZABICYCLO[4.3.0]NONANE AND INTERMEDIATE THEREOF Kaneka Corporation (JP) 2012-02-29 EP disclosed
US-5952503-A Method for producing optically-active 2-piperazinecarboxylic acid derivatives TORAY INDUSTRIES, INC. (JP) 1999-09-14 US disclosed
EP-0906906-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2-PIPERAZINECARBOXYLIC ACID DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1999-04-07 EP disclosed