Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338235 | 0.95 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL2454460 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL11660153 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL9859901 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL18050209 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| Methane SCHEMBL9753821 | 0.81 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL28918727 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL1743418 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1GAAPOLB | |
| SCHEMBL21994251 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1GAAALDH1A1 | |
| SCHEMBL31558918 | 0.79 | SMN1; SMN2 (0.80) | SMN1; SMN2RAB9ANPC1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893441-B1 | Process for the production of pyridyl methylisothiocyanate | BAYER CROPSCIENCE AG (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-4044127-A | RICE, TOMATOES, APPLES, RICE BLAST, APPLE SCAB, TOMATO LATE BLIGHT | AMERICAN CYANAMIDE COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4029652-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-06-14 | — | — | US | disclosed |