Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988897 | 1.00 | ABL1 (0.51) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL6989039 | 0.83 | ALB (0.43) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL6989042 | 0.83 | ALB (0.43) | NPC1RAB9AMAPTGAAKDM4E | |
| SCHEMBL6990816 | 0.82 | ALB (0.47) | MAPTKDM4EALBERN1PTGS1 | |
| SCHEMBL6990822 | 0.82 | ALB (0.47) | MAPTKDM4EALBERN1PTGS1 | |
| SCHEMBL6995099 | 0.79 | ADORA2A (0.56) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL6995096 | 0.79 | ADORA2A (0.56) | ABL1ABCB1BCRMAPTKDM4E | |
| SCHEMBL6989986 | 0.77 | ALB (0.51) | NPC1RAB9AMAPTKDM4EMAPK1 | |
| SCHEMBL6989987 | 0.77 | ALB (0.51) | NPC1RAB9AMAPTKDM4EMAPK1 | |
| SCHEMBL6992891 | 0.74 | ALB (0.46) | RAB9AMAPTKDM4EALBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-5728709-A | COAGULANTS AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |