Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989042 | 1.00 | ALB (0.43) | ALBCCNB2CDK1CDK4CCNB1 | |
| SCHEMBL6988897 | 0.83 | ABL1 (0.51) | ALBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6988902 | 0.83 | ABL1 (0.51) | ALBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6993349 | 0.80 | MEN1 (0.52) | ALBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6993353 | 0.80 | MEN1 (0.52) | ALBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6990816 | 0.76 | ALB (0.47) | ALBMEN1KMT2AERN1MAPT | |
| SCHEMBL6990822 | 0.76 | ALB (0.47) | ALBMEN1KMT2AERN1MAPT | |
| SCHEMBL6994514 | 0.75 | SRD5A2 (0.51) | ALBPTGER3NPC1RAB9AMEN1 | |
| SCHEMBL6994512 | 0.75 | SRD5A2 (0.51) | ALBPTGER3NPC1RAB9AMEN1 | |
| SCHEMBL6995099 | 0.74 | ADORA2A (0.56) | ALBCDK4CCND1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768311-B1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-0768311-A1 | PYRROLOCARBAZOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |