Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826951 | 1.00 | SMYD3 (0.39) | SMYD3ALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL6826955 | 1.00 | SMYD3 (0.39) | SMYD3ALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL6826953 | 1.00 | SMYD3 (0.39) | SMYD3ALDH1A1L3MBTL1GAAMGAM | |
| SCHEMBL22776971 | 0.90 | SMYD3 (0.44) | SMYD3ALDH1A1GAAMGAMSI | |
| SCHEMBL851434 | 0.88 | GAA (0.43) | ALDH1A1L3MBTL1GAAMGAMSI | |
| SCHEMBL19728295 | 0.84 | GAA (0.43) | SMYD3ALDH1A1GAAMGAMSI | |
| SCHEMBL1881523 | 0.84 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1GAAMGAMSI | |
| SCHEMBL6881676 | 0.83 | BRD4 (0.39) | SMYD3ALDH1A1L3MBTL1KMT2APOLB | |
| SCHEMBL6881684 | 0.83 | BRD4 (0.39) | SMYD3ALDH1A1L3MBTL1KMT2APOLB | |
| SCHEMBL6881679 | 0.83 | BRD4 (0.39) | SMYD3ALDH1A1L3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |