Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987664 | 0.87 | SIGMAR1 (0.39) | SIGMAR1TMEM97HCRTR2HCRTR1 | |
| SCHEMBL6988968 | 0.79 | SIGMAR1 (0.36) | SIGMAR1TMEM97HPGDHCRTR2GAA | |
| SCHEMBL6994527 | 0.79 | SIGMAR1 (0.36) | SIGMAR1TMEM97HPGDHCRTR2GAA | |
| SCHEMBL1222778 | 0.79 | SIGMAR1 (0.36) | SIGMAR1TMEM97HPGDHCRTR2GAA | |
| SCHEMBL1222781 | 0.79 | SIGMAR1 (0.36) | SIGMAR1TMEM97HPGDHCRTR2GAA | |
| SCHEMBL28580670 | 0.75 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL27756338 | 0.75 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL13691987 | 0.75 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL12540247 | 0.75 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL27756333 | 0.75 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930312-B1 | Production method of optically active amino alcohols | JAPAN TOBACCO INC (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6197966-B1 | REACTING MESOEPOXIDE WITH AMINE TO FORM 1,3-DIOXEPANE DERIVATIVE; ACID CATALYSIS; RING CONTRACTION TO 1,3-DIOXOLANE | JAPAN TOBACCO INC. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0930312-A1 | Production method of optically active amino alcohols | Japan Tobacco Inc. (JP) | 1999-07-21 | — | — | EP | disclosed |