Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988972 | 0.87 | SIGMAR1 (0.38) | SIGMAR1TMEM97HCRTR2HCRTR1 | |
| SCHEMBL646069 | 0.86 | TMEM97 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1TSHR | |
| SCHEMBL9347312 | 0.86 | TMEM97 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1TSHR | |
| SCHEMBL13528036 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL21210136 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL13528035 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL13528037 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL21210139 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL31335170 | 0.82 | SIGMAR1 (0.41) | SIGMAR1TMEM97HCRTR2HCRTR1POLB | |
| SCHEMBL1222024 | 0.81 | TMEM97 (0.38) | SIGMAR1TMEM97HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930312-B1 | Production method of optically active amino alcohols | JAPAN TOBACCO INC (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6197966-B1 | REACTING MESOEPOXIDE WITH AMINE TO FORM 1,3-DIOXEPANE DERIVATIVE; ACID CATALYSIS; RING CONTRACTION TO 1,3-DIOXOLANE | JAPAN TOBACCO INC. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0930312-A1 | Production method of optically active amino alcohols | Japan Tobacco Inc. (JP) | 1999-07-21 | — | — | EP | disclosed |