Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.49 |
| ▸ | TUBB | P07437 | 4/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985223 | 0.77 | ERN1 (0.49) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6040526 | 0.77 | TNFRSF1A (0.55) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5571761 | 0.75 | TNFRSF1A (0.81) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5571769 | 0.75 | TNFRSF1A (0.81) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7058562 | 0.75 | TNFRSF1A (0.57) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5575689 | 0.73 | TNFRSF1A (0.67) | TNFRSF1ASMN1; SMN2TP53LMNACYP3A4 | |
| SCHEMBL4728380 | 0.72 | TNFRSF1A (0.49) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6094342 | 0.72 | TNFRSF1A (0.49) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6112015 | 0.72 | TNFRSF1A (0.72) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6092533 | 0.71 | MAPT (0.53) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330448-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | Atherogenics, Inc. (US) | 2003-07-30 | — | — | EP | disclosed |
| WO-2001098291-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | ATHEROGENICS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |