Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMG1 | Q96Q15 | 9/20 | 0.67 |
| ▸ | MTOR | P42345 | 5/20 | 0.67 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 8/20 | 0.51 |
| ▸ | CDK1 | P06493 | 5/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 6/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095910 | 0.82 | SMG1 (0.63) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL28751600 | 0.80 | SMG1 (0.60) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL6987209 | 0.79 | SMG1 (0.62) | SMG1MTORCDK2CDK1CDK4 | |
| SCHEMBL2328646 | 0.76 | CLK1 (0.65) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL27116471 | 0.75 | CLK1 (0.66) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL4901590 | 0.75 | ABL1 (0.67) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL4892529 | 0.74 | CLK1 (0.65) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL3512029 | 0.73 | AURKA (0.62) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL25336406 | 0.72 | CAMK2D (0.69) | SMG1MTORCLK1CLK2DYRK1A | |
| SCHEMBL27115596 | 0.72 | SYK (0.65) | SMG1MTORCLK1CLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349849-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | Syngenta Participations AG (CH) | 2003-10-08 | — | — | EP | claimed |
| WO-2002053560-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-07-11 | — | — | WO | claimed |