Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.65 |
| ▸ | CLK2 | P49760 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 2/20 | 0.62 |
| ▸ | CDK2 | P24941 | 3/20 | 0.59 |
| ▸ | CDK4 | P11802 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | IDH2 | P48735 | 2/20 | 0.53 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116471 | 0.87 | CLK1 (0.66) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL4901590 | 0.86 | ABL1 (0.67) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL4892529 | 0.86 | CLK1 (0.65) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL2331086 | 0.84 | PIK3CG (0.70) | DYRK1ASMG1CDK2FLT1FLT4 | |
| SCHEMBL2322043 | 0.84 | PIK3CG (0.70) | DYRK1ASMG1CDK2FLT1FLT4 | |
| SCHEMBL14088796 | 0.83 | AURKA (0.72) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL25336406 | 0.83 | CAMK2D (0.69) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL30554563 | 0.83 | CAMK2D (0.69) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL27115596 | 0.83 | SYK (0.65) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL3514514 | 0.83 | AURKA (0.62) | CLK1CLK2DYRK1ACLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | claimed |
| CN-102216286-A | Substituted (pyridyl)-azinylamine derivatives as plant protection agents | BAYER CROPSCIENCE SA | 2011-10-12 | — | — | CN | claimed |
| EP-2356102-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| CN-102216286-A | Substituted (pyridyl)-azinylamine derivatives as plant protection agents | BAYER CROPSCIENCE SA | 2011-10-12 | — | — | CN | disclosed |
| EP-2356102-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | PRXL2A, AZI2, PIR | CLK1 4109/4885CLK2 3757/4885DYRK1A 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.