SCHEMBL698926

SCHEMBL698926

O=C1N=c2cncnc2=N1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30790285 0.74
SCHEMBL31337161 0.71 EGFR (0.33)
SCHEMBL31061724 0.71
SCHEMBL30783034 0.67
SCHEMBL28287224 0.65
SCHEMBL876323 0.63 EGFR (0.33)
SCHEMBL322054 0.62 CDC25B (0.31) CDC25B
SCHEMBL19207495 0.61
SCHEMBL30753848 0.61 CDC25B (0.33) CDC25B
SCHEMBL247141 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4531856-B1 BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION ALK ABELLO AS (DK) 2026-04-22 EP claimed
CN-120081848-A Imidazo-containing pyrimidinone derivative, and preparation method and application thereof 贵州大学 2025-06-03 CN claimed
EP-4554678-A1 PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2025-05-21 EP claimed
EP-3801538-B1 TLR7 AGONISTS PRIMMUNE THERAPEUTICS INC (US) 2024-10-02 EP claimed
WO-2024013205-A1 PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2024-01-18 WO claimed
CN-114106000-B Imidazo [4,5-d ] pyrimidinone tricyclic derivative and antitumor application thereof 中国科学院新疆理化技术研究所 2023-11-24 CN claimed
CN-115448921-B Imidazolidine pyrimidinone compounds and use thereof in treatment of HsClpP mediated diseases 四川大学 2023-08-01 CN claimed
CN-114106000-A Imidazo [4,5-d ] pyrimidone tricyclic derivative and anti-tumor application 中国科学院新疆理化技术研究所 2022-03-01 CN claimed
CN-113604148-A Nano SiO2Modified quadruple hydrogen bond type self-repairing polyurethane coating and preparation method thereof 深圳市博仲实业有限公司 2021-11-05 CN claimed
CN-113164618-A Methods and compositions for treating diseases with immunostimulatory conjugates 希沃尔拜克治疗公司 2021-07-23 CN claimed
US-6432642-B1 A DETECTOR, TARGET, CLAMPS AND HYBRIDIZATION PE CORPORATION (NY) 2002-08-13 US claimed
EP-1155027-A2 SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS PE Corporation (NY) (US) 2001-11-21 EP claimed
US-6316230-B1 ENZYMATICALLY EXTENDING A PNA(PEPTIDE NUCLEIC ACID)-DNA CHIMERA IN PRESENCE OF TEMPLATE NUCLEIC ACID, POLYMERASE AND PRIMER EXTENSION REAGENT APPLERA CORPORATION 2001-11-13 US claimed
US-6316610-B2 Hybrid stabilization PE CORPORATION (NY) 2001-11-13 US claimed
EP-1141387-A2 BINARY PROBE AND CLAMP COMPOSITION AND METHODS FOR TARGET HYBRIDIZATION DETECTION PE Corporation (NY) (US) 2001-10-10 EP claimed
US-6297016-B1 ENZYMATICALLY LIGATING A PEPTIDE NUCLEIC ACID-DNA CHIMERIC PROBE TO SECOND PROBE WHEN PROBES ARE HYBRIDIZED ADJACENT TO EACH OTHER ON A TEMPLATE NUCLEIC ACID APPLERA CORPORATION 2001-10-02 US claimed
US-20010014735-A1 Labelled oligonucleotides synthesized on solid-supports PE CORPORATION (NY) 2001-08-16 US claimed
US-6255476-B1 REACTING A LABELLED SOLID SUPPORT OF GIVEN FORMULA TO REMOVE AN ACID CLEAVABLE PROTECTING GROUP, ADDING A 5'-PHOSPHORAMIDITE, 3'-PROTECTED NUCLEOSIDE AND AN ACTIVATOR TO FROM A BOND PE CORPORATION (NY) 2001-07-03 US claimed
WO-2000050432-A2 SYNTHESIS OF LABELLED OLIGONUCLEOTIDES ON SOLID-SUPPORTS PE CORPORATION (NY) (US) 2000-08-31 WO claimed
WO-2000041549-A2 BINARY PROBE AND CLAMP COMPOSITION AND METHODS FOR TARGET HYBRIDIZATION DETECTION PE CORPORATION (NY) (US) 2000-07-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010014735-A1 Labelled oligonucleotides synthesized on solid-supports NSUN2, TST, NSUN3 CDC25B 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.