Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485205 | 0.87 | CNR1 (0.55) | CNR1TRPV1PPARGPPARACHRM2 | |
| SCHEMBL792125 | 0.84 | GLA (0.70) | CNR1GLAKMT2AHDAC3HDAC4 | |
| SCHEMBL793534 | 0.84 | GLA (0.70) | GLAKMT2ATRPV1HDAC3HDAC4 | |
| SCHEMBL27422506 | 0.82 | CNR1 (0.67) | CNR1TRPV1GLSCHRM2CHRM1 | |
| SCHEMBL798802 | 0.82 | THRB (0.60) | CNR1GLAKMT2ATRPV1HDAC3 | |
| SCHEMBL7643257 | 0.82 | CNR1 (0.63) | CNR1TRPV1CHRM2CHRM1CHRM3 | |
| SCHEMBL3939774 | 0.81 | PPARA (0.51) | CNR1PPARGPPARACHRM2CHRM1 | |
| SCHEMBL27087783 | 0.80 | HDAC3 (0.56) | CNR1GLAKMT2AHDAC3HDAC4 | |
| SCHEMBL15466955 | 0.80 | HDAC3 (0.59) | CNR1GLAKMT2AHDAC3HDAC4 | |
| SCHEMBL12885093 | 0.79 | SPR (0.62) | GLAKMT2AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |