Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995984 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL6993565 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL6994490 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL8036758 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6991013 | 0.81 | MAPT (0.43) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL6992272 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL16336874 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL14976877 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL14977089 | 0.70 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 | |
| SCHEMBL2685197 | 0.70 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |