Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989310 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL6995984 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL6994490 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL8036758 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL6991013 | 0.80 | MAPT (0.43) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL6989668 | 0.78 | KDM4E (0.49) | ALDH1A1KMT2AMAPTHTTHSD17B10 | |
| SCHEMBL6992272 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL6995377 | 0.74 | MAPT (0.41) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL7090950 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL912513 | 0.68 | HPGD (0.61) | ALDH1A1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |