Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 4/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186393 | 0.89 | PTPN1 (0.50) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6187415 | 0.88 | PTPN1 (0.48) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6886206 | 0.88 | PTPN1 (0.49) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6182857 | 0.81 | MEN1 (0.55) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6182863 | 0.81 | MEN1 (0.55) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6185038 | 0.80 | MGLL (0.48) | — | |
| SCHEMBL5386765 | 0.78 | MAOA (0.54) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL5386774 | 0.78 | MAOA (0.54) | PTPN1HPGDAKR1B1POLBMEN1 | |
| SCHEMBL6255495 | 0.77 | MGLL (0.52) | MEN1KMT2ARAB9A | |
| SCHEMBL5397253 | 0.77 | MEN1 (0.53) | PTPN1HPGDAKR1B1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |