Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991463 | 0.99 | TSHR (0.51) | ALDH1A1KMT2AMAPTMEN1HIF1A | |
| SCHEMBL7081753 | 0.89 | LMNA (0.52) | ALDH1A1KMT2AMAPTMEN1HIF1A | |
| SCHEMBL7083930 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTMEN1HIF1A | |
| SCHEMBL7076644 | 0.88 | HIF1A (0.48) | ALDH1A1KMT2AMAPTMEN1HIF1A | |
| SCHEMBL19708081 | 0.82 | CYP1A2 (0.57) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19707310 | 0.79 | CYP1A2 (0.54) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL7082012 | 0.78 | CYP2D6 (0.59) | ALDH1A1HIF1ACYP2D6TSHRHSD17B10 | |
| SCHEMBL30666841 | 0.77 | HTT (0.43) | ALDH1A1KMT2AMAPTMEN1HIF1A | |
| SCHEMBL3954627 | 0.76 | CYP1A2 (0.61) | ALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL2991144 | 0.76 | CYP1A2 (0.61) | ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1443160-A | N-substituted-1-amino-1,1-dialkyl carboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-09-17 | — | — | CN | disclosed |
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | ALDH1A1 1315/4885KMT2A 2153/4885MAPT 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.